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These are the excellent presentations from the Children with Cancer UK sponsored childhood cancer session organised by Professor Denis Henshaw for the 8th Princess Chulabhorn International Scientific Congress held in Thailand in November 2016.

Our highly successful 2017 conference concentrated on the latest in advanced treatments research. Our 2018 Conference is primarily concentrating on causal factors and prevention but we will also have updates on our current treatment projects and some other forms of treatment.

We are not planning to offer one-day tickets and so it is necessary for you to book for the whole 3-day conference if you wish to attend. We are highly subsidising the cost of attending this stimulating and paradigm-changing conference. For charges, please see "Registration" page.


Day 1 - The Metabolic Roots of Cancer and Introduction to causal factors

Doors open from 08.00         Programme starts 09.15         Drinks reception and Poster viewing 17.00–19.30

The main programe will start with a challenging Keynote Address by a leading work public health doctor and Ramazzini Fellow (details to be posted here later)

This will be followed by a introductory talk by Travis Christofferson, MS, author of "Tripping over the Truth", giving a pertinent and critical history of cancer research over the past 150 years and outlining setting the scene for re-assessment of the underlying metabolic cause of most cancers. To see his earlier 2016 South Florida University meeting presentation, see: Cancer 2.0: A Paradigm Shift. His excellent book, "Tripping over the Truth"(2017 Ed) is available from booksellers.

A major presentation by Thomas Seyfried, PhD, follows entitled "Cancer as a metabolic disease, including the origin, management and prevention of cancer". Dr Seyfried has taught and conducted research in the fields of neurogenetics and neurochemistry and cancer for more than 25 years at Yale University and Boston College. He This will be followed by a short discussion. Dr Seyfried has published over 150 scientific papers on related topics and written a key textbook "Cancer as a Metabolic Disease" (Wiley, 2012). He also gave a presentation in 2016 at the South Florida University meeting: Cancer as a mitochondrial metabolic disease.

After lunch, Children with Cancer UK's Scientific Director, and Ramazzini Fellow, Professor Denis Henshaw will give a presentation on "Primary prevention: Link from metabolic and epigenetic roots of cancer to exposure from environmental agents and lifestyle factors. The need for both epidemiological and mechanistic evidence".

This will be followed by Dr Kurt Straif, Head of Monographs, International Agency for Research on Cancer (IARC, WHO), who will address "The multi-causal nature of Cancer and the IARC Monograph assessments".

Professor Catherine Metayer,MD,PhD, of UC Berkeley School of Public Health and Chair of the Center for Integrative Research on Childhood Leukaemia and other cancers and the Environment (CIRCLE) and the International Consortium (CLIC), will talk about identifying and reducing exposure to risk factors associated with childhood cancer.

From 16:00 hrs there will time to view and discuss the scientific posters with a drinks and canapes reception from 17:00 and further poster viewing until 18:30 hrs.


Day 2 - The Environmental Causes of Cancer – The Evidence

Doors open from 08.15         Programme starts 09.00 and ends at 17.00

Day 2 will include the following talks:

Dr Fiorella Belpoggi,MD, will present the results of the latest European Ramazzini Foundation long-term animal research into the effects, including cancer, of exposure to electromagnetic fields originating from electricity and cellular telephone technology. Dr Belpoggi has dedicated her career to the identification of industrial and environmental carcinogens. As vice scientific director and chief of pathology at the European Foundation of Oncology and Environmental Sciences, European Ramazzini Foundation, Bologna, Italy, she has led experimental studies of widely diffused substances, including benzene, methyl tert-butyl ether and other octane enhancers, ionising radiation and aspartame. Dr Belpoggi has also conducted studies on the chemoprevention of tumours, by using both natural and artificial compounds.

Professor Sosterios Kyrtopoulos, Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation. He will talk on "Transplacental carcinogenesis and risk to children: epigenetic profiles of environmental exposures and his progress on cord blood epigenetics". Professor Kyrtopoulos was the Head of the Laboratory of Chemical Carcinogenesis and Genetic Toxicology and the Unit of Environmental Toxicology. Recent project include the EU FP6 NewGeneris project (Newborns and Genotoxic exposure risks); cordination of the EU FP7 EnviroGenomarkers project (Genomics biomarkers of environmental health) 2009-2013; and EU FP7 Exposomics project (Enhanced exposure assessment and omic profiling for high priority environmental exposures in Europe) 2012-2016.

Professor Roberta Mckean-Cowdin, Clinical Preventive Medicine, University of Southern California, USA. "Brain Tumours in children and young people – what do we know about risk factors".

Professor Jos Kleinjans, Head of Toxicogenomics Department, Environmental Health Sciences, Maastricht Univerisity, Netherlands. "Dietary and air-borne carcinogens and risk of childhood cancer". Professor Kleinjans coordinated the EU FP6 NewGeneris European prospective mother-child study: Development and application of biomarkers of dietary exposure to genotoxic and immunotoxic chemicals and of biomarkers of early effects, using mother-child birth cohorts and biobanks.

Professor Marco Vinceti, Director, Research Centre in Environmental, Genetic and Nutritional Epidemiology of Modena and Reggio Emilia University (CREAGEN). "Epidemiology and environmental risk factors (including air pollution) of childhood cancer".

Dr Mark Miller, Assoc. Clinical Professor of Paediatrics and Internal Medicine, UCSF. Director of the Children’s Environmental Health Program at California EPA. "Results from the various CLIC studies (Pesticides, house dust, etc. details TBC)" Also presenting an introduction to the clinicians’ "Pediatric Environmental Health Toolkit" resource.

Professor Richard Stevens, Community Medicine and Health Care, University of Connecticut. "Light at night, melatonin, and the importance of circadian rhythms". Professor Stevens researches the health impact of artificial light pollution.

Professor Cathy Vaillancourt, INRS-Institut Armand-Frappier, Université du Québec. "Role of melatonin as a protective agent in utero". My unit studies the effects of environmental contaminants and season of pregnancy on placental functions and fetal development. Our research hypothesis is that exposure at certain seasonal and climatic environmental factors, and persistent environmental pollutants, such as metals and organo-chlorides (polycyclic biphenyls and pesticides) during pregnancy could induce important alterations in the mechanisms of regulation of the human placenta and by consequence on fetal development. More specifically our studies focus on placental dopaminergic, serotoninergic and melatoninergic systems.


Day 3 - Treating and Preventing Cancer – The Way Forward

Doors open from 08.15         Programme starts 09.00         Conference closes and ends at 16.30

Day 3 is still being planned, but will include the following talks:

A series of presentations updating the progress from some of Children with Cancer UK's currently funded major projects including SMPaeds, INSTINCT and the Brain Tumour Consortium Initiative.

Professor Louis Chesler, Institure of Cancer Research, London. "Progress report on the start of large SMPaeds initiative". Dr Chesler is a leading figure in the development of new targetted drugs for hard-to-treat childhood cancers.

Professor Russell Reiter, Department of Cellular and Structural Biology University of Texas Health Science Center at San Antonio. "The importance of melatonin in cancer treatment and prevention". Dr. Reiter is the Editor-in-Chief of the Journal of Pineal Research and on the Editorial Board of 7 other journals. He is the recipient of numerous awards including three honorary doctor of medicine degrees and, most recently, the Presidential Distinguished Scholar Award from UTHSCSA.

Dr Erica Mallery-Blythe,MD, Physicians' Health Initiative for Radiation and Environment (PHIRE). "Cancer-related and biological justifications for minimising child ionising and non-ionising radiation exposures".

Some short oral talks by up to 3 of the best Poster Presentations.

Chris Woollams, Founder and Director of Cancer Active (Regd Charity). "A Holistic Approach to treating cancer and examples of Cancer Active successes".

A Panel Led discussion with delegate questions from the floor

Raporteur report and take-home messages from the conference

Conclusion


This page was last updated 2nd April 2018

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