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These are the excellent presentations from the Children with Cancer UK sponsored childhood cancer session organised by Professor Denis Henshaw for the 8th Princess Chulabhorn International Scientific Congress held in Thailand in November 2016.

Cancer in Children and Young People

International Scientific and Medical Conference 2018

12th-14th September 2018, Westminster, London

a landmark conference examining the way we understand cancer,
exploring the way forward within the full US NIH definition of Precision Medicine

Preventing Cancer  -  Improving Treatment  -  Reducing suffering  -  Saving Lives  -  Saving Money

Registration is now closed. The conference will be free live video streamed

from 08:45 Wednesday 12th September. Click here to see it:

Children with Cancer UK You Tube Channel

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Main Themes:

  Day One: The Metabolic and Epigenetic Roots of Cancer - The Evidence
     Top world scientists bring us up to date with the latest evidence
The need for both epidemiological and mechanistic evidence
     The multi-causal nature of cancer and international collaborative research
  Day Two: The Environmental Causes of Cancer - The Evidence
     Air, food, diet, chemicals, infections, radiation, lifestyle
  Day Three: Treating and Preventing Cancer - The Way Forward
     Updates on the treatment-related research projects that we fund
     Kinder, more integrated, treatments to reduce suffering
     What to do about causal factors

Cancer research - where now?  Signposts towards the future

There have been some excellent improvements in cancer treatment with more patients being cured or living longer lives and with less long-term adverse effects from treatment, but the overall war against cancer is stalling. Drugs targeted against specific genetic and proteomic markers will play an important role in the future. However, ten years of intense work on The Cancer Genome Atlas sequenced 10,000 malignant tumours and discovered about 10,000,000 cancer related mutations. (TCGA, 2006-2015)

A systematic study of cancer drugs approved by the European Medicines Agency in recent years found that most had no evidence of better survival or quality of life (doi:10.1136/bmj.j4530).

Fiona Goodlee, Editor in Chief of the BMJ recently wrote (5th Oct. 2017):
"The few drugs with evidence of benefit achieved only marginal gains."

The January 2018 issue of the Royal Society of Medicine Journal has a long article by Charles Swanton (Francis Crick Institute and UCL) which starts:
"The cost of cancer drugs since 1965 have increased from US$100 per month to US $10,000 per month. Unfortunately many of these novel anti-cancer drugs are not working any better than they were 40 or 50 years ago. If we take the 12 years between 2002 and 2014, of the 71 anti-cancer drugs that were approved, 23 of these had no overall survival benefit."

The percentage of children and young people with cancer who survive more than ten years has increased little since 2000, and those who do survive often have considerable personal health and life challenges. It is clear that we need to develop improved approaches and integrate changes that have been shown to help.

This challenging conference will explore evidence-based possibilities for change

© 2018 Children with Cancer UK
51 Great Ormond Street, London, WC1N 3JQ
Tel: 020 7404 0808,     Registered Charity Number: 298405
Inaugurated by Diana, Princess of Wales